Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12945116 | 0.88 | CA12 (0.31) | CA12CA1CA9CYP3A4 | |
| SCHEMBL13871201 | 0.85 | CA12 (0.39) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL12909291 | 0.82 | CA12 (0.36) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL27392258 | 0.78 | CYP3A4 (0.41) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL30829199 | 0.78 | CYP3A4 (0.41) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL8133606 | 0.75 | MEN1 (0.41) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL12945233 | 0.74 | CA12 (0.32) | CA12CA1CA9 | |
| SCHEMBL30829200 | 0.73 | CYP3A4 (0.65) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL27392150 | 0.73 | CYP3A4 (0.65) | CA12CA1CA9MEN1USP2 | |
| SCHEMBL7599603 | 0.71 | MEN1 (0.38) | CA12CA1CA9MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868147-B2 | substantially no fluorescent before the cleavage but highly fluorescent after the cleavage; traps a target substance such as an enzyme and emits fluorescence | Nagano, Tetsuo (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7524974-B2 | Fluorescent probe | Nagano, Tetsuo (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080014602-A1 | Fluorescent Probe | SEKISUI MEDICAL CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |