⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128106 | 0.88 | — | — | |
| SCHEMBL128735 | 0.88 | — | — | |
| SCHEMBL8358942 | 0.86 | TP53 (0.58) | — | |
| SCHEMBL127712 | 0.86 | TP53 (0.58) | — | |
| SCHEMBL28955996 | 0.82 | TP53 (0.33) | — | |
| SCHEMBL8396898 | 0.77 | — | — | |
| SCHEMBL1472491 | 0.71 | — | — | |
| SCHEMBL10882332 | 0.71 | TP53 (0.42) | — | |
| SCHEMBL2246490 | 0.71 | — | — | |
| SCHEMBL15769664 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875001-B1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-09 | — | — | EP | disclosed |
| US-9434695-B2 | Nitrogenous heterocyclic derivatives and their application in drugs | SUNSHINE LAKE PHARMA CO., LTD (CN) | 2016-09-06 | — | — | US | disclosed |
| CN-103570630-B | Nitrogen heterocyclic derivative and the application in medicine thereof | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |
| EP-2875001-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-05-27 | — | — | EP | disclosed |
| US-20150087639-A1 | Nitrogenous Heterocyclic Derivatives And Their Application In Drugs | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-03-26 | — | — | US | disclosed |
| CN-103570630-A | Heterocyclic nitrogen derivative and application thereof in medicines | GUANGDONG HEC PHARMACEUTICAL | 2014-02-12 | — | — | CN | disclosed |
| WO-2014012360-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-01-23 | — | — | WO | disclosed |
| CN-102086211-B | Aromatic heterocyclic compounds serving as protein kinase inhibitor | SHENZHEN HEC INDUSTRY DEV CO LTD | 2013-09-11 | — | — | CN | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| CN-101374844-B | Pyrrolopyridazinone compound | UBE INDUSTRIES | 2012-10-24 | — | — | CN | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-102086211-A | Aromatic heterocyclic compounds serving as protein kinase inhibitor | SHENZHEN HEC INDUSTRY DEV CO LTD | 2011-06-08 | — | — | CN | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| CN-101096354-A | Method for oriented synthesis of unsaturated conjugated alcohol | CHONGQING HUABANG PHARMACY LTD (CN) | 2008-01-02 | — | — | CN | disclosed |
| CN-1972920-A | Arylalkyl piperazine derivatives for the treatment of conditions ameliorated by monoamine reuptake including vasomotor symptoms | WYETH CORP (US) | 2007-05-30 | — | — | CN | disclosed |