Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547696 | 1.00 | CPN1 (0.47) | CPN1CPB2SHBGKCNH2SLC6A1 | |
| SCHEMBL23997493 | 0.87 | CPN1 (0.34) | CPN1CPB2SHBGKCNH2HCAR2 | |
| SCHEMBL8603745 | 0.87 | — | — | |
| SCHEMBL11142498 | 0.87 | — | — | |
| SCHEMBL23838574 | 0.83 | CPN1 (0.36) | CPN1CPB2KMT2A | |
| SCHEMBL23997605 | 0.82 | KCNH2 (0.32) | KCNH2TSHRKDM4EHCAR2 | |
| SCHEMBL18611150 | 0.82 | CPN1 (0.50) | CPN1CPB2KCNH2SLC6A1SLC6A11 | |
| SCHEMBL29333164 | 0.82 | CPN1 (0.46) | CPN1CPB2KCNH2SLC6A1SLC6A11 | |
| SCHEMBL29332964 | 0.82 | CPN1 (0.50) | CPN1CPB2KCNH2SLC6A1SLC6A11 | |
| SCHEMBL15133700 | 0.82 | CPN1 (0.42) | CPN1CPB2SHBGKCNH2SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284179-A2 | Inhibitors of cancer cell, T-cell and keratinocyte proliferation | 4SC AG (DE) | 2011-02-16 | — | — | EP | disclosed |