Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228132 | 0.92 | KCNH2 (0.75) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL12920574 | 0.92 | KCNH2 (0.72) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL1228810 | 0.90 | KCNH2 (0.70) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL1228678 | 0.89 | KCNH2 (0.94) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL1227766 | 0.89 | KCNH2 (0.78) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL1227152 | 0.88 | KCNH2 (0.76) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL14801644 | 0.88 | KCNH2 (0.80) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL14801643 | 0.88 | KCNH2 (0.80) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL3195951 | 0.88 | KCNH2 (0.76) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C | |
| SCHEMBL14801215 | 0.88 | KCNH2 (0.76) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014776-A1 | NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2011-02-03 | — | — | WO | disclosed |