Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.81 |
| ▸ | FLT3 | P36888 | 3/20 | 0.79 |
| ▸ | KDR | P35968 | 8/20 | 0.56 |
| ▸ | PLK4 | O00444 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 2/20 | 0.44 |
| ▸ | FRK | P42685 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.44 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.44 |
| ▸ | SRMS | Q9H3Y6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292303 | 0.92 | BTK (0.84) | BTKFLT3KDR | |
| SCHEMBL1292731 | 0.92 | BTK (0.84) | BTKFLT3KDR | |
| SCHEMBL1292450 | 0.90 | BTK (0.79) | BTKFLT3KDRPLK4ROCK2 | |
| SCHEMBL1292630 | 0.90 | BTK (0.84) | BTKFLT3KDR | |
| SCHEMBL30098550 | 0.90 | BTK (1.00) | BTKFLT3KDRPLK4ROCK2 | |
| SCHEMBL17218629 | 0.90 | BTK (1.00) | BTKFLT3KDRPLK4ROCK2 | |
| SCHEMBL17218915 | 0.90 | BTK (1.00) | BTKFLT3KDRPLK4ROCK2 | |
| SCHEMBL29897289 | 0.90 | BTK (1.00) | BTKFLT3KDRPLK4ROCK2 | |
| SCHEMBL1292688 | 0.89 | BTK (0.80) | BTKFLT3KDR | |
| SCHEMBL1292718 | 0.89 | BTK (0.80) | BTKFLT3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |