SCHEMBL129253

SCHEMBL129253

COc1cc(OC)c2cc(O)c(-c3cc(OC)c(O)c(OC)c3)[o+]c2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD38 P28907 7/20 0.70
MAOA P21397 1/20 0.68
DPP4 P27487 1/20 0.68
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
GLO1 Q04760 4/20 0.44
EGFR P00533 2/20 0.44
KDR P35968 2/20 0.44
SNCA P37840 2/20 0.44
EP300 Q09472 2/20 0.44
CREBBP Q92793 2/20 0.44
ABL1 P00519 1/20 0.41
BCR P11274 1/20 0.41
SMPD3 Q9NY59 1/20 0.39
OR51E2 Q9H255 2/20 0.38
APP P05067 1/20 0.37
USP2 O75604 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527028 0.91 CD38 (0.84) CD38MAOADPP4ALDH1A1TSHR
SCHEMBL29435846 0.91 CD38 (0.84) CD38MAOADPP4ALDH1A1TSHR
SCHEMBL131502 0.88 CD38 (0.84) CD38MAOADPP4ALDH1A1TSHR
SCHEMBL29382950 0.84 CD38 (0.84) CD38MAOADPP4ALDH1A1TSHR
Malvidin SCHEMBL21739 0.82 CD38 (1.00) CD38MAOADPP4ALDH1A1TSHR
Malvidin SCHEMBL29406694 0.82 CD38 (1.00) CD38MAOADPP4ALDH1A1TSHR
Malvidin SCHEMBL30683334 0.81 DPP4 (1.00) CD38MAOADPP4ALDH1A1TSHR
Malvidin SCHEMBL29640416 0.81 DPP4 (1.00) CD38MAOADPP4ALDH1A1TSHR
Malvidin SCHEMBL308690 0.81 DPP4 (1.00) CD38MAOADPP4ALDH1A1TSHR
SCHEMBL12194290 0.79 CD38 (0.77) CD38MAOADPP4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292765-B1 Flavonoid 3',5' Hydroxylase gene sequences and uses therefor SUNTORY HOLDINGS LTD (JP) 2013-06-19 EP disclosed
EP-2292764-B1 Flavonoid 3',5' hydroxylase gene sequences and uses therefor SUNTORY HOLDINGS LTD (JP) 2013-05-29 EP disclosed
US-8445748-B2 Flavonoid 3′,5′ hydroxylase gene sequences and uses therefor SUNTORY HOLDINGS LIMITED (JP) 2013-05-21 US disclosed
US-8288612-B2 Genetically modified plants with altered inflorescence SUNTORY HOLDINGS LIMITED (JP) 2012-10-16 US disclosed
EP-2096172-B1 Genetic sequences having methyltransferase activity and uses therefor SUNTORY HOLDINGS LTD (JP) 2012-04-04 EP disclosed
EP-1546340-B1 FLAVONOID 3',5'HYDROXYLASE GENE SEQUENCES AND USES THEREFOR SUNTORY HOLDINGS LTD (JP) 2012-03-07 EP disclosed
EP-1478753-B1 FLAVENOID METHYLTRANSFERASE FROM TORENIA AND USES THEREFOR INTERNAT FLOWERS DEVELOPMENTS PROPRIETARY LTD (AU) 2011-03-23 EP disclosed
EP-2292765-A1 Flavonoid 3',5' Hydroxylase gene sequences and uses therefor International Flower Developments PTY LTD (AU) 2011-03-09 EP disclosed
EP-2292764-A1 Flavonoid 3',5' hydroxylase gene sequences and uses therefor International Flower Developments PTY LTD (AU) 2011-03-09 EP disclosed
US-20110008523-A1 GENETIC SEQUENCES HAVING METHYLTRANSFERASE ACTIVITY AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 2011-01-13 US disclosed
WO-2009062259-A1 GENETICALLY MODIFIED PLANTS WITH ALTERED INFLORESCENCE INTERNATIONAL FLOWER DEVELOPMENTS PTY LTD (AU) 2009-05-22 WO disclosed
EP-1546340-A4 FLAVANOID 3',5'HYDROXYLASE GENE SEQUENCES AND USES THEREFOR INTERNAT FLOWERS DEVELOPMENTS (AU) 2007-08-08 EP disclosed
US-20070150984-A1 Genetic sequences having methyltransferase activity and uses therefor INTERNATIONAL FLOWER DEVELOPMENTS PTY.LTD. OF COLLINGWOOD (AU) 2007-06-28 US disclosed
EP-1478753-A4 GENETIC SEQUENCES HAVING METHYLTRANSFERASE ACTIVITY AND USES THEREFOR INTERNAT FLOWERS DEVELOPMENTS (AU) 2007-03-28 EP disclosed
US-20070033674-A1 Flavanoid 3',5' hydroxylase gene sequences and uses therefor SUNTORY HOLDINGS LIMITED (JP) 2007-02-08 US disclosed
EP-1546340-A1 FLAVANOID 3',5'HYDROXYLASE GENE SEQUENCES AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) 2005-06-29 EP disclosed
EP-1478753-A1 GENETIC SEQUENCES HAVING METHYLTRANSFERASE ACTIVITY AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) 2004-11-24 EP disclosed
WO-2004020637-A9 FLAVONOID 3',5'HYDROXYLASE GENE SEQUENCES AND USES THEREFOR INT FLOWER DEV PTY LTD (AU) 2004-06-03 WO disclosed
WO-2004020637-A1 FLAVONOID 3',5'HYDROXYLASE GENE SEQUENCES AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 2004-03-11 WO disclosed
WO-2003062428-A1 GENETIC SEQUENCES HAVING METHYLTRANSFERASE ACTIVITY AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS PTY LTD (AU) 2003-07-31 WO disclosed