Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12850523 | 0.85 | IRAK4 (0.65) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL12850549 | 0.75 | PIK3CA (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL26174568 | 0.73 | DYRK1A (0.65) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26174767 | 0.72 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL26174694 | 0.72 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGLRRK2 | |
| SCHEMBL26175773 | 0.72 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL12276557 | 0.72 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 | |
| SCHEMBL29313995 | 0.72 | IRAK4 (0.66) | IRAK4 | |
| SCHEMBL26174731 | 0.71 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26175734 | 0.71 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022439-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE, INC. (US) | 2011-02-24 | — | — | WO | disclosed |