SCHEMBL1293183

SCHEMBL1293183

C=CC(=O)OCC(Cl)CCl

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.55
ALDH1A1 P00352 4/20 0.43
TP53 P04637 4/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 1/20 0.39
THRB P10828 2/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9602823 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1170750 0.82 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27522724 0.81 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28399730 0.80
SCHEMBL132195 0.79 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17335735 0.78
SCHEMBL6758124 0.78
SCHEMBL28313930 0.77 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2927236 0.77
SCHEMBL28005755 0.76 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
US-4500628-A IRRADIATING FILM CONSISTING OF POLYMER AND ORGANOSILICON MONOMER AT&T BELL LABORATORIES (US) 1985-02-19 US claimed
EP-0017032-B1 METHOD OF PRODUCING A SOLID STATE DEVICE BY DIFFERENTIAL PLASMA ETCHING OF RESISTS Western Electric Company, Incorporated (US) 1984-02-15 EP claimed
US-4400235-A Etching apparatus and method BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1983-08-23 US claimed
US-4396704-A Solid state devices produced by organometallic plasma developed resists BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1983-08-02 US claimed
US-4232110-A FORMATION OF NEGATIVES BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1980-11-04 US claimed
EP-0017032-A2 Method of producing a solid state device by differential plasma etching of resists Western Electric Company, Incorporated (US) 1980-10-15 EP claimed
US-4225664-A X-ray resist containing poly(2,3-dichloro-1-propyl acrylate) and poly(glycidyl methacrylate-co-ethyl acrylate) BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1980-09-30 US claimed
WO-1980001978-A1 SOLID STATE DEVICES BY DIFFERENTIAL PLASMA ETCHING OF RESISTS WESTERN ELECTRIC CO (US) 1980-09-18 WO claimed
EP-0015459-A1 Article comprising a negative X-ray resist containing poly(2,3-dichloro-1-propyl acrylate) and poly(glycidyl methacrylate-co-ethyl acrylate) and method using this resist Western Electric Company, Incorporated (US) 1980-09-17 EP claimed
WO-1980001847-A1 NEGATIVE X-RAY RESIST CONTAINING POLY(2,3-DICHLORO-1-PROPYL ACRYLATE)AND POLY(GLYCIDYL METHACRYLATE-CO-ETHYL ACRYLATE) WESTERN ELECTRIC CO (US) 1980-09-04 WO claimed
US-4136225-A CROSSLINKED POLYMER OF DICHLOROPROPYL ACRYLATE BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1979-01-23 US claimed
US-4061829-A Negative resist for X-ray and electron beam lithography and method of using same BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1977-12-06 US claimed
JP-3007774-A None JP disclosed
CN-122037662-A Water-based gloss oil with flame color anti-counterfeiting function, and preparation method and detection method thereof 上海高邦印刷材料有限公司 2026-05-15 CN disclosed
US-20160038388-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF INC (US) 2016-02-11 US disclosed
US-4136225-A CROSSLINKED POLYMER OF DICHLOROPROPYL ACRYLATE BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1979-01-23 US disclosed
US-4061829-A Negative resist for X-ray and electron beam lithography and method of using same BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1977-12-06 US disclosed
US-4022750-A Process for the production of a halogen-containing arcylic synthetic fiber improved in flame retardancy AMERICAN CYANAMID COMPANY (US) 1977-05-10 US disclosed
US-3983185-A Halogen containing polyester resins having improved smoke-resistance HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 TSHR 3749/4885ALDH1A1 457/4885TP53 879/4885
US-20160038388-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 TSHR 3749/4885ALDH1A1 457/4885TP53 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.