⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131127 | 0.86 | ATM (0.68) | — | |
| SCHEMBL5069215 | 0.84 | HCAR2 (0.60) | — | |
| SCHEMBL11207249 | 0.83 | — | — | |
| SCHEMBL10669903 | 0.83 | — | — | |
| SCHEMBL126105 | 0.83 | HCAR2 (0.54) | — | |
| SCHEMBL8896227 | 0.82 | HCAR2 (0.61) | — | |
| SCHEMBL8895622 | 0.82 | HCAR2 (0.61) | — | |
| SCHEMBL8896165 | 0.82 | HCAR2 (0.61) | — | |
| SCHEMBL1569307 | 0.82 | HCAR2 (0.61) | — | |
| SCHEMBL5634629 | 0.82 | HCAR2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942617-B | Alpha-tetra-substituted chiral alkynone compound and preparation method and application thereof | 北京大学深圳研究生院 | 2021-08-20 | — | — | CN | claimed |
| US-20180020662-A1 | Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | US | claimed |
| EP-3256448-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-12-20 | — | — | EP | claimed |
| WO-2016128365-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | WO | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0969721-A1 | FUNGICIDAL BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR COOLING LUBRICANTS | BAYER AG (DE) | 2000-01-12 | — | — | EP | claimed |
| WO-1998039968-A1 | FUNGICIDAL BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR COOLING LUBRICANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | claimed |
| EP-0851899-A1 | BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR USE IN ANTI-FOULING APPLICATIONS | BAYER AG (DE) | 1998-07-08 | — | — | EP | claimed |
| WO-1997011131-A1 | BENZOTHIOPHENE-2-CARBOXAMIDE-S,S-DIOXIDES FOR USE IN ANTI-FOULING APPLICATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-27 | — | — | WO | claimed |
| EP-0359979-B1 | AMINOMETHYLHETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES | BAYER AG (DE) | 1992-12-30 | — | — | EP | claimed |
| EP-0512349-A1 | Benzothiophene-2-carboxamide-S,S-dioxides | BAYER AG (DE) | 1992-11-11 | — | — | EP | claimed |
| EP-0484776-A1 | Arylsubstituted alkyliden-nitrogenheterocycles | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0281842-B1 | AMINOMETHYL-HETEROCYCLES | BAYER AG (DE) | 1991-07-17 | — | — | EP | claimed |
| US-5010101-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | claimed |
| US-4985421-A | Fungicidal substituted dioxolanylethylamine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | claimed |
| EP-0359979-A1 | Aminomethylheterocyclic compounds, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-03-28 | — | — | EP | claimed |
| EP-0355597-A1 | Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| US-4851405-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | claimed |
| EP-0281842-A1 | Aminomethyl-heterocycles | BAYER AG (DE) | 1988-09-14 | — | — | EP | claimed |