Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909639 | 0.94 | NR1I2 (0.55) | NR1I2CYP2E1ACACB | |
| SCHEMBL939738 | 0.94 | NR1I2 (0.55) | NR1I2CYP2E1ACACB | |
| SCHEMBL12949676 | 0.89 | NR1I2 (0.34) | NR1I2OPRD1ACACB | |
| SCHEMBL938026 | 0.84 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL12909638 | 0.84 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL12945479 | 0.83 | NR1I2 (0.41) | NR1I2CYP2E1ACACB | |
| SCHEMBL12909646 | 0.83 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL940230 | 0.83 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL12909630 | 0.82 | NR1I2 (0.55) | NR1I2CYP2E1 | |
| SCHEMBL937365 | 0.82 | NR1I2 (0.55) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011303-A1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |