Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949798 | 0.91 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL1004666 | 0.90 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL12949607 | 0.89 | MCHR1 (0.67) | MCHR1 | |
| SCHEMBL12949692 | 0.88 | MCHR1 (0.83) | MCHR1 | |
| SCHEMBL12949589 | 0.87 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL12949841 | 0.86 | MCHR1 (0.74) | MCHR1 | |
| SCHEMBL12949606 | 0.85 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL11437586 | 0.83 | MCHR1 (0.76) | MCHR1 | |
| SCHEMBL1004051 | 0.83 | MCHR1 (0.71) | MCHR1 | |
| SCHEMBL12927575 | 0.83 | MCHR1 (0.81) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003005-A1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-06 | — | — | WO | disclosed |