Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954085 | 0.92 | GSK3B (0.51) | GSK3BNAMPTDRD3DRD2CHEK1 | |
| SCHEMBL13118902 | 0.91 | GSK3B (0.67) | GSK3BNAMPT | |
| SCHEMBL13289048 | 0.87 | GSK3B (0.59) | GSK3BCHEK1 | |
| SCHEMBL13288627 | 0.85 | GSK3B (0.52) | GSK3BCHEK1 | |
| SCHEMBL13288839 | 0.85 | GSK3B (0.56) | GSK3BCHEK1 | |
| SCHEMBL12953866 | 0.84 | GSK3B (0.54) | GSK3BCHEK1 | |
| SCHEMBL13288814 | 0.84 | GSK3B (0.61) | GSK3BCHEK1 | |
| SCHEMBL13305370 | 0.84 | GSK3B (0.61) | GSK3BCHEK1 | |
| SCHEMBL12953848 | 0.84 | GSK3B (0.61) | GSK3BCHEK1 | |
| SCHEMBL13288625 | 0.84 | GSK3B (0.56) | GSK3BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720882-B1 | PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2011-01-05 | — | — | EP | disclosed |