Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.51 |
| ▸ | VNN1 | O95497 | 7/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119209 | 0.92 | GSK3B (0.64) | GSK3BCCNE1CDK2 | |
| SCHEMBL14307156 | 0.89 | GSK3B (0.50) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL14043163 | 0.88 | GSK3B (0.51) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL14545254 | 0.88 | GSK3B (0.51) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL14301571 | 0.88 | GSK3B (0.53) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL13304610 | 0.87 | GSK3B (0.59) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL14301228 | 0.86 | GSK3B (0.53) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL12954098 | 0.85 | GSK3B (0.51) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL13304611 | 0.85 | GSK3B (0.59) | GSK3BVNN1CHEK1CCNE1CDK2 | |
| SCHEMBL13305284 | 0.85 | GSK3B (0.59) | GSK3BVNN1CHEK1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720882-B1 | PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2011-01-05 | — | — | EP | disclosed |