Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301776 | 0.93 | CDK2 (0.51) | CDK2GSK3BEPHB4AURKARPS6KB1 | |
| SCHEMBL12954120 | 0.92 | CDK2 (0.49) | CDK2GSK3BEPHB4RAB9AAURKA | |
| SCHEMBL13289245 | 0.92 | CDK2 (0.49) | CDK2GSK3BEPHB4RAB9AMEN1 | |
| SCHEMBL14301775 | 0.91 | CDK2 (0.49) | CDK2GSK3BAURKAAURKB | |
| SCHEMBL13289563 | 0.91 | CDK2 (0.50) | CDK2GSK3BEPHB4MEN1KMT2A | |
| SCHEMBL13121781 | 0.91 | CDK2 (0.64) | CDK2GSK3B | |
| SCHEMBL13289340 | 0.90 | CDK2 (0.48) | CDK2GSK3BRAF1 | |
| SCHEMBL12954205 | 0.90 | CDK2 (0.49) | CDK2GSK3BEPHB4AURKAPDPK1 | |
| SCHEMBL13289332 | 0.90 | CDK2 (0.51) | CDK2GSK3BMAPT | |
| SCHEMBL13289326 | 0.90 | CDK2 (0.47) | CDK2GSK3BEPHB4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720882-B1 | PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORP (US) | 2011-01-05 | — | — | EP | disclosed |