Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | BMX | P51813 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961943 | 0.93 | BTK (0.69) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL1038343 | 0.92 | BTK (0.69) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL13078377 | 0.84 | BTK (0.60) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL13044179 | 0.83 | BTK (0.66) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL12956034 | 0.80 | BTK (0.71) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL12956349 | 0.79 | BTK (0.66) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL13044139 | 0.79 | BTK (0.72) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL12955977 | 0.79 | BTK (0.66) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL12956162 | 0.78 | BTK (0.67) | BTKEGFRBMXJAK3CD69 | |
| SCHEMBL13044107 | 0.78 | BTK (0.67) | BTKEGFRBMXJAK3CD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079726-B1 | SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |