⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282801 | 0.79 | — | — | |
| SCHEMBL453909 | 0.78 | — | — | |
| SCHEMBL9357255 | 0.77 | TAAR1 (0.56) | — | |
| SCHEMBL8671494 | 0.77 | TAAR1 (0.71) | — | |
| SCHEMBL2090609 | 0.75 | — | — | |
| Ethylene SCHEMBL27825954 | 0.74 | — | — | |
| SCHEMBL2096400 | 0.74 | TAAR1 (0.54) | — | |
| SCHEMBL8687460 | 0.74 | — | — | |
| SCHEMBL8343615 | 0.74 | CYP17A1 (0.56) | — | |
| SCHEMBL479477 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134016-A | Tricyclic heterocycles | 默克专利股份公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115867534-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115803025-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115515959-A | Tricyclic heterocycles as TEAD binders | 默克专利股份公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114174263-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2022-03-11 | — | — | CN | claimed |
| CN-112812133-B | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2022-03-11 | — | — | CN | claimed |
| CN-112812133-A | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2021-05-18 | — | — | CN | claimed |
| CN-111954541-A | Polymersomes comprising soluble encapsulated antigens, methods of making and uses thereof | ACM生物实验室私人有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-106749318-B | A kind of organic field effect tube material and its synthetic method and application based on oxa- condensed ring class | 苏州大学 | 2019-01-08 | — | — | CN | claimed |
| CN-106467547-B | Polycyclic-based non-fullerene solar cell receptor material and preparation method and application thereof | 苏州大学 | 2018-07-03 | — | — | CN | claimed |
| EP-0315574-A2 | Renin inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-10 | — | — | EP | claimed |
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | claimed |
| EP-0252299-A2 | Use of 12-amino-pyridazino[4',5':3,4]pyrrolo[2,1-a]isoquinolines in the preparation of cardioprotective and neuroprotective agents | BOEHRINGER INGELHEIM KG (DE) | 1988-01-13 | — | — | EP | claimed |
| EP-0179855-A4 | DOPAMINE AGONISTS. | NELSON RES & DEV COMPANY (US) | 1986-08-21 | — | — | EP | claimed |
| EP-0179855-A1 | DOPAMINE AGONISTS. | NELSON RES & DEV (US) | 1986-05-07 | — | — | EP | claimed |
| US-4584303-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1986-04-22 | — | — | US | claimed |
| EP-0160422-A1 | N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds | Anaquest, Inc. (US) | 1985-11-06 | — | — | EP | claimed |
| WO-1985004582-A1 | NOVEL DOPAMINE AGONISTS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1985-10-24 | — | — | WO | claimed |
| US-4540691-A | Dopamine agonists and use thereof | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1985-09-10 | — | — | US | claimed |
| US-4409226-A | ANTIULCER AGENTS | SCHERING CORPORATION (US) | 1983-10-11 | — | — | US | claimed |