Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12960877 | 0.90 | GALR3 (0.44) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8516911 | 0.90 | EGFR (0.49) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8491653 | 0.90 | EGFR (0.49) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8506874 | 0.89 | EGFR (0.48) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL12960878 | 0.84 | GALR3 (0.48) | EGFRABCG2HTTGALR3NR2F2 | |
| SCHEMBL8497655 | 0.84 | NR2F2 (0.50) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL9609149 | 0.83 | GALR3 (0.45) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8516559 | 0.83 | GALR3 (0.45) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8516838 | 0.81 | GALR3 (0.50) | EGFRABCG2HTTTSHRGALR3 | |
| SCHEMBL8497433 | 0.81 | GALR3 (0.43) | EGFRABCG2HTTTSHRGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |