Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068699 | 0.92 | BTK (0.82) | BTK | |
| SCHEMBL1068791 | 0.92 | BTK (0.70) | BTK | |
| SCHEMBL1066569 | 0.92 | BTK (0.70) | BTK | |
| SCHEMBL1068821 | 0.91 | BTK (0.69) | BTK | |
| SCHEMBL1069547 | 0.90 | BTK (0.67) | BTK | |
| SCHEMBL1069049 | 0.90 | BTK (0.67) | BTK | |
| SCHEMBL1068795 | 0.87 | BTK (0.66) | BTK | |
| SCHEMBL1069957 | 0.85 | BTK (0.70) | BTK | |
| SCHEMBL1066488 | 0.84 | BTK (0.68) | BTK | |
| SCHEMBL1069047 | 0.84 | BTK (0.82) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270200-A2 | Kinase inhibitors, and methods of using and identifying kinase inhibitors | CGI Pharmaceuticals, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2008033858-A2 | KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |