Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12803159 | 1.00 | TYMP (0.41) | TYMPBCHEPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL12803158 | 1.00 | TYMP (0.41) | TYMPBCHEPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL12516421 | 1.00 | TYMP (0.41) | TYMPBCHEPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL24433796 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL25948647 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL26002231 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL25873786 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL22960862 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL16326503 | 0.93 | TYMP (0.41) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 | |
| SCHEMBL15060980 | 0.91 | TYMP (0.39) | TYMPPRKAG1PRKAA1PRKAB1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252027-A1 | Method For Rapidly Evaluating Performance Of Short Interfering RNA With Novel Chemical Modifications | BANK OF AMERICA, N.A. | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252027-A1 | Method For Rapidly Evaluating Performance Of Short Interfering RNA With Novel Chemical Modifications | NSUN2, NSUN3, SNRPE | TYMP 459/4885BCHE 4715/4885PRKAG1 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.