Ethylene Glycol

Ethylene Glycol

SCHEMBL1296491

CC(C)CCCOC(=O)C1CCCCC1C(=O)O.OCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC18A2 Q05940 1/20 0.36
PPARG P37231 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ACE P12821 1/20 0.33
PEPD P12955 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1296806 0.96 TP53 (0.39) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL1296461 0.91 TP53 (0.38) TP53CYP3A4GAARAB9ASMN1; SMN2
Ethylene Glycol SCHEMBL1296967 0.91 PPARG (0.42) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL5512096 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL5519996 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL5525257 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL1297245 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL5523910 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL5519589 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2
SCHEMBL1297249 0.90 TP53 (0.37) TP53CYP3A4GAARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
US-20110265693-A1 Use Of Polyols And Cyclohexane Polycarboxylic Acid Derivatives For The Removal Of Dust From Chemical Construction Products Construction Research & Tecnology GMBH (DE) 2011-11-03 US disclosed
US-7337913-B2 Single piece closure device made of PVC BASF AKTIENGESELLSCHAFT (DE) 2008-03-04 US disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed