Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.73 |
| ▸ | MAOB | P27338 | 4/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966206 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15425027 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15425028 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12813922 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL16309046 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15423787 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15423786 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL16309044 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL16309047 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12965717 | 1.00 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135113-A2 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-10-04 | — | — | WO | disclosed |