⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749182 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL4985705 | 0.97 | — | — | |
| SCHEMBL27658044 | 0.97 | — | — | |
| SCHEMBL29089384 | 0.97 | — | — | |
| SCHEMBL28846932 | 0.97 | — | — | |
| Methylene Chloride SCHEMBL28135615 | 0.92 | — | — | |
| Ethylene SCHEMBL27571393 | 0.92 | — | — | |
| SCHEMBL1484132 | 0.90 | — | — | |
| SCHEMBL29015963 | 0.90 | — | — | |
| SCHEMBL12501178 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306112-B2 | Biphenyl tetradentate phosphite compound: preparation method and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2022-04-19 | — | — | US | claimed |
| CN-112159313-A | Preparation method of big steric-hindrance bi-phenol skeleton and phosphonite ligand thereof | 惠州凯特立斯科技有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-110498874-A | A kind of alkoxyl magnesium particle, and its preparation method and application | CHINA PETROLEUM & CHEM CORP | 2019-11-26 | — | — | CN | claimed |
| CN-110498872-A | A kind of alkoxyl magnesium particle, and its preparation method and application | CHINA PETROLEUM & CHEM CORP | 2019-11-26 | — | — | CN | claimed |
| CN-103172644-B | A kind of preparation method of medicinal artemisinin | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-12-23 | — | — | CN | claimed |
| CN-103193791-B | A kind of synthetic method of medicinal artemisinin | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-103172645-B | High-efficiency synthesis method of artemisinin | UNIV SHANGHAI JIAOTONG | 2015-05-20 | — | — | CN | claimed |
| CN-103193791-A | High-efficiency synthesizing method of medical artemisinin | UNIV SHANGHAI JIAOTONG | 2013-07-10 | — | — | CN | claimed |
| CN-103172644-A | Method for preparing medicinal artemisinin | UNIV SHANGHAI JIAOTONG | 2013-06-26 | — | — | CN | claimed |
| CN-103172645-A | High-efficiency synthesis method of artemisinin | UNIV SHANGHAI JIAOTONG | 2013-06-26 | — | — | CN | claimed |
| EP-4559919-A1 | TRICYCLIC-CONTAINING MACROCYCLIC COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2025-05-28 | — | — | EP | disclosed |
| CN-115244043-B | Benzimidazolone cinnamamide derivatives as TRPV1 antagonists and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| EP-4095133-B1 | BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT | JMACKEM CO LTD (KR) | 2024-07-24 | — | — | EP | disclosed |
| WO-2024017380-A1 | TRICYCLIC-CONTAINING MACROCYCLIC COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2024-01-25 | — | — | WO | disclosed |
| US-4038299-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4005126-A | Preparation of haloalkyl esters | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4005125-A | Preparation of haloalkyl esters | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-3989839-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3966820-A | ANALGESICS, ANTIINFLAMMATORY, ANTIPYRETICS | SYNTEX (U.S.A.) INC. (US) | 1976-06-29 | — | — | US | disclosed |