SCHEMBL1296985

SCHEMBL1296985

CCCCCCCCCCCCCC=CC=CC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)C=CC=CCCCCCCCCCCCCC

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.49
SELP P16109 1/20 0.46
P2RY10 O00398 6/20 0.45
GPR34 Q9UPC5 1/20 0.45
FABP3 P05413 1/20 0.45
ENPP2 Q13822 1/20 0.43
LPAR1 Q92633 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1296680 1.00 PLA2G2C (0.49) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL235778 0.99 PLA2G2C (0.48) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL31318032 0.99 PLA2G2C (0.48) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL25252924 0.99 PLA2G2C (0.48) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL30976336 0.99 PLA2G2C (0.48) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL30094354 0.93 PLA2G2C (0.52) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL19595704 0.93 PLA2G2C (0.52) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL31468233 0.93 PLA2G2C (0.52) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL29928151 0.93 PLA2G2C (0.52) PLA2G2CSELPP2RY10GPR34FABP3
SCHEMBL1296508 0.92 SELP (0.57) SELPP2RY10GPR34FABP3ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269942-A1 ANTIBODIES MODIFIED WITH HYDROPHOBIC MOLECULE DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20100209490-A1 IMMUNOLIPOSOME INDUCING APOPTOSIS INTO CELL EXPRESSING DEATH DOMAIN-CONTAINING RECEPTOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-08-19 US disclosed
EP-2184355-A1 ANTIBODY MODIFIED WITH HYDROPHOBIC MOLECULE Daiichi Sankyo Company, Limited (JP) 2010-05-12 EP disclosed
EP-2177230-A1 IMMUNOLIPOSOME INDUCING APOPTOSIS INTO CELL EXPRESSING DEATH DOMAIN-CONTAINING RECEPTOR Daiichi Sankyo Company, Limited (JP) 2010-04-21 EP disclosed