Ethylene Glycol

Ethylene Glycol

SCHEMBL1297153

CCCCCC(CCC)COC(=O)C1CCCCC1C(=O)O.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
CYP3A4 P08684 3/20 0.34
TSHR P16473 2/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.32
SLC18A2 Q05940 1/20 0.32
NAAA Q02083 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP14 P50281 1/20 0.31
CA2 P00918 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1296709 0.96 PRSS1 (0.36) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1296707 0.91 PRSS1 (0.40) PRSS1PRSS2PRSS3CYP3A4TSHR
Ethylene Glycol SCHEMBL1297154 0.89 CYP3A4 (0.47) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1297159 0.89 PRSS1 (0.35) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1297281 0.87 TSHR (0.40) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1296662 0.86 ZDHHC7 (0.38) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1296566 0.86 PRSS1 (0.36) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1297025 0.86 PRSS1 (0.36) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1296708 0.86 CHRM2 (0.38) PRSS1PRSS2PRSS3CYP3A4TSHR
SCHEMBL1296981 0.86 CHRM2 (0.38) PRSS1PRSS2PRSS3CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
US-20110265693-A1 Use Of Polyols And Cyclohexane Polycarboxylic Acid Derivatives For The Removal Of Dust From Chemical Construction Products Construction Research & Tecnology GMBH (DE) 2011-11-03 US disclosed
US-7337913-B2 Single piece closure device made of PVC BASF AKTIENGESELLSCHAFT (DE) 2008-03-04 US disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed