Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984772 | 0.84 | AOC3 (0.42) | AOC3SLC6A3CYP19A1HIF1AADRA2A | |
| SCHEMBL19645455 | 0.82 | ESR1 (0.50) | SLC6A3HIF1AADRA2AADRA2CLMNA | |
| SCHEMBL13523886 | 0.80 | CYP19A1 (0.38) | SLC6A3CYP19A1HIF1ATDP1ALDH1A1 | |
| SCHEMBL16199252 | 0.80 | HIF1A (0.38) | AOC3CYP19A1HIF1AADRA2AADRA2C | |
| SCHEMBL1173366 | 0.80 | AOC3 (0.59) | AOC3SLC6A3HIF1AADRA2AADRA2C | |
| SCHEMBL7531733 | 0.80 | AOC3 (0.59) | AOC3SLC6A3HIF1AADRA2AADRA2C | |
| SCHEMBL2678379 | 0.78 | CYP19A1 (0.42) | AOC3SLC6A3CYP19A1HIF1ALMNA | |
| SCHEMBL13014888 | 0.78 | KDM4E (0.38) | AOC3SLC6A3HIF1AADRA2AADRA2C | |
| SCHEMBL13014615 | 0.77 | CYP19A1 (0.32) | AOC3CYP19A1HIF1AKDM4ETDP1 | |
| SCHEMBL2407454 | 0.75 | GRIA4 (0.42) | SLC6A3CYP19A1TDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258684-A1 | Monoazo compounds | CLARIANT INTERNATIONAL LTD (CH) | 2010-12-08 | — | — | EP | disclosed |
| WO-2010130378-A1 | MONOAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130383-A1 | MONOAZO COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251381-A1 | Monoazo compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251321-A1 | Monoazo compounds | Clariant International Ltd. (CH) | 2010-11-17 | — | — | EP | disclosed |
| EP-2098573-A2 | Basic monoazo compounds | Clariant International Ltd. (CH) | 2009-09-09 | — | — | EP | disclosed |