SCHEMBL129846

SCHEMBL129846

NC1CCOc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 1/20 0.46
ICAM1 P05362 1/20 0.46
ITGAL P20701 1/20 0.46
LMNA P02545 2/20 0.41
CRHBP P24387 2/20 0.41
CRHR2 Q13324 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HTT P42858 1/20 0.41
MAP3K14 Q99558 1/20 0.38
DPP4 P27487 1/20 0.36
SSTR4 P31391 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
HTR2A P28223 2/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30563663 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL29858755 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL2627039 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL193981 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL1163533 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
SCHEMBL29764040 1.00 ITGB2 (0.46) ITGB2ICAM1ITGALLMNACRHBP
Hydrochloric Acid SCHEMBL29484136 0.98 ITGB2 (0.44) ITGB2ICAM1ITGALLMNACRHBP
Hydrochloric Acid SCHEMBL432891 0.98 ITGB2 (0.44) ITGB2ICAM1ITGALLMNACRHBP
Hydrochloric Acid SCHEMBL29484132 0.98 ITGB2 (0.44) ITGB2ICAM1ITGALLMNACRHBP
Hydrochloric Acid SCHEMBL431787 0.98 ITGB2 (0.44) ITGB2ICAM1ITGALLMNACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984967-B1 NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS IAF BIOCHEM INT (CA) 2004-02-25 EP claimed
US-20010031765-A1 Antiviral compounds BIOCHEM PHARMA INC. 2001-10-18 US claimed
US-6255318-B1 CYTOMEGLO VIRUS BIOCHEM PHARMA INC. (CA) 2001-07-03 US claimed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-12630516-B2 Compounds NRG THERAPEUTICS LTD. (GB) 2026-05-19 US disclosed
EP-4705281-A1 COMPOUNDS FOR TREATING CANCER Genesis Molecular AI, Inc. (US) 2026-03-11 EP disclosed
EP-4688785-A1 5-AMINO-6, 8-DIHYDRO-1H-FURO [3, 4-D] PYRROLO [3, 2-B] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AS MTA-COOPERATIVE INHIBITORS OF PRMT5 Beone Medicines I GmbH (CH) 2026-02-11 EP disclosed
US-20260007680-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2026-01-08 US disclosed
US-20260001876-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2026-01-01 US disclosed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
EP-4208442-B1 MPTP INHIBITORS NRG THERAPEUTICS LTD (GB) 2025-10-22 EP disclosed
CN-1169429-A Sulfamine-substituted benzodihydopyran, preparation method, use as medicine or diagnostic reagent and medicine containing same HOECHST AG (DE) 1998-01-07 CN disclosed
WO-1997034894-A1 NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS BIOCHEM PHARMA INC. (CA) 1997-09-25 WO disclosed
US-5035739-A PLANT GROWTH REGULATORS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-07-30 US disclosed
US-4919705-A PLANT GROWTH REGULATORS IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-04-24 US disclosed
EP-0305529-A1 TRIFLUOROMETHANESULFONAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-03-08 EP disclosed
US-4238501-A INSECTICIDES, MITICIDES, PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
US-4237162-A MITICIDES, LARVACIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed
US-4115407-A N-Benzyl-4-chromanamines MORTON-NORWICH PRODUCTS, INC. (US) 1978-09-19 US disclosed
US-4093799-A N-arylidene-4-chromanamines MORTON-NORWICH PRODUCTS, INC. (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630516-B2 Compounds CYP4B1, CYP1B1, NR4A1 ITGB2 441/4885ICAM1 2828/4885ITGAL 1203/4885
US-20260001876-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE4B, PDE7A ITGB2 2054/4885ICAM1 4770/4885ITGAL 3208/4885
US-20260007680-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B ITGB2 3532/4885ICAM1 4841/4885ITGAL 3976/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B ITGB2 3086/4885ICAM1 4773/4885ITGAL 3501/4885
US-20010031765-A1 Antiviral compounds ZC3HAV1, IFNAR1, EIF2AK2 ITGB2 4787/4885ICAM1 3471/4885ITGAL 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.