Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985971 | 0.91 | AKT1 (0.79) | AKT1AKT2 | |
| SCHEMBL12986277 | 0.91 | AKT1 (0.70) | AKT1AKT2 | |
| SCHEMBL15679371 | 0.90 | AKT1 (0.72) | AKT1AKT2 | |
| SCHEMBL12985903 | 0.89 | AKT1 (0.71) | AKT1AKT2 | |
| SCHEMBL12985935 | 0.89 | AKT1 (0.71) | AKT1AKT2 | |
| SCHEMBL12985953 | 0.88 | AKT1 (0.63) | AKT1AKT2 | |
| SCHEMBL12986166 | 0.88 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL12985638 | 0.86 | AKT1 (0.72) | AKT1AKT2 | |
| SCHEMBL12986061 | 0.86 | AKT1 (0.73) | AKT1AKT2 | |
| SCHEMBL17353379 | 0.85 | AKT1 (0.79) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206185-B2 | Imidazopyridazines as Akt kinase inhibitors | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| EP-2694510-B1 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS | BAYER IP GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| EP-2694510-A1 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS | Bayer Intellectual Property GmbH (DE) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012136776-A1 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-10-11 | — | — | WO | disclosed |