SCHEMBL129871

SCHEMBL129871

CC#CBr.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL484143 0.94
SCHEMBL7052459 0.94
SCHEMBL28278920 0.89
Ammonia Solution, Strong SCHEMBL29078776 0.89
SCHEMBL6051713 0.68
SCHEMBL6812435 0.68
SCHEMBL17921336 0.65
SCHEMBL18681 0.60
SCHEMBL667648 0.60
SCHEMBL3994247 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114044753-A Small molecular compound with anti-tumor metastasis function and preparation method thereof 广州市朝利良生物科技有限公司 2022-02-15 CN claimed
EP-0128839-B1 LABELLED STEROIDS, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES, THEIR USE IN THE LOCALIZATION OF THE GLUCOCORTICOID RECEPTORS AND IN THE DOSAGE OF THE NUMBER OF BINDING SITES ROUSSEL-UCLAF (FR) 1989-05-17 EP claimed
US-4664850-A Novel radioactive steroids ROUSSEL UCLAF (FR) 1987-05-12 US claimed
EP-4656240-A1 NAPHTHYRIDINONE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER Novartis AG (CH) 2025-12-03 EP disclosed
US-12459893-B2 Indole-ynone mediated benzoannulation process for the preparation of carbazoles, carbazomycin A, calothrixin B and staurosporinone COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-11-04 US disclosed
EP-4436662-B1 NAPHTHYRIDINONE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER NOVARTIS AG (CH) 2025-09-17 EP disclosed
US-20250270210-A1 BCL-2 Inhibitor BEIGENE, LTD. (KY) 2025-08-28 US disclosed
US-20250214989-A1 NAPHTHYRIDINONE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER NOVARTIS AG (CH) 2025-07-03 US disclosed
US-12286430-B2 Bcl-2 inhibitor BEIGENE, LTD. (KY) 2025-04-29 US disclosed
US-20250066584-A1 PHOTOINITIATORS, COMPOSITIONS, AND METHODS OF FORMING AN OBJECT QUADRATIC 3D, INC. 2025-02-27 US disclosed
EP-4508492-A1 PHOTOINITIATORS, COMPOSITIONS, AND METHODS OF FORMING AN OBJECT Quadratic 3D, Inc. (US) 2025-02-19 EP disclosed
US-4086249-A Tetramethyl chromanyl pentane amide HOFFMANN-LA ROCHE INC. (US) 1978-04-25 US disclosed
US-4076739-A Synthesis of vitamin E HOFFMANN-LA ROCHE INC. (US) 1978-02-28 US disclosed
US-4045475-A Optically active alcohols and lower esters thereof HOFFMANN-LA ROCHE INC. (US) 1977-08-30 US disclosed
US-4029678-A Asymmetric synthesis HOFFMANN-LA ROCHE INC. (US) 1977-06-14 US disclosed
US-4016178-A Synthesis of vitamin E HOFFMANN-LA ROCHE INC. (US) 1977-04-05 US disclosed
US-4012391-A 11β-Alkyl-2-azaestratrienes and intermediates G. D. SEARLE & CO. (US) 1977-03-15 US disclosed
US-4000169-A ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 1976-12-28 US disclosed
US-3965143-A 16-Oxygenated prostanoic acid derivatives G. D. SEARLE & CO. (US) 1976-06-22 US disclosed
US-3959322-A Synthesis of 13-alkyl-gon-4-ones Smith, Herchel (US) 1976-05-25 US disclosed