Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12988587 | 0.91 | MEN1 (0.76) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL27782774 | 0.88 | RECQL (0.62) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL414186 | 0.86 | RECQL (0.60) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL4343691 | 0.84 | EPHX1 (0.60) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| Hydrochloric Acid SCHEMBL320450 | 0.81 | NAMPT (0.57) | RECQLSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL23646221 | 0.81 | EPHX1 (0.66) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL23646267 | 0.81 | EPHX1 (0.66) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL23646198 | 0.81 | EPHX1 (0.66) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL23646271 | 0.81 | EPHX1 (0.66) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL31372224 | 0.81 | EPHX1 (0.66) | RECQLSMN1; SMN2KMT2AMEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305113-A1 | Substituted Imidazopyridazines as Lipid Kinase Inhibitors | CAPRARO HANS-GEORG | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305113-A1 | Substituted Imidazopyridazines as Lipid Kinase Inhibitors | PI4KA, PIK3CA, PIK3CB | RECQL 2479/4885SMN1; SMN2 4165/4885KMT2A 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.