Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 20/20 | 0.84 |
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.84 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195906 | 1.00 | LPAR1 (0.84) | LPAR1LPAR3HRH1 | |
| SCHEMBL14710921 | 0.94 | LPAR1 (0.74) | LPAR1LPAR3HRH1 | |
| SCHEMBL13195375 | 0.93 | LPAR1 (0.81) | LPAR1LPAR3HRH1 | |
| SCHEMBL14709195 | 0.93 | LPAR1 (0.82) | LPAR1LPAR3HRH1 | |
| SCHEMBL17077064 | 0.92 | LPAR1 (0.98) | LPAR1LPAR3HRH1 | |
| SCHEMBL17077063 | 0.92 | LPAR1 (0.98) | LPAR1LPAR3HRH1 | |
| SCHEMBL12989672 | 0.92 | LPAR1 (1.00) | LPAR1LPAR3HRH1 | |
| SCHEMBL12989395 | 0.92 | LPAR1 (1.00) | LPAR1LPAR3HRH1 | |
| SCHEMBL12989963 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3HRH1 | |
| SCHEMBL12989447 | 0.91 | LPAR1 (0.98) | LPAR1LPAR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138648-A1 | COMPOSITIONS AND METHODS FOR MODULATING LPA RECEPTORS | IRM LLC (BM) | 2012-10-11 | — | — | WO | disclosed |