Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | POLB | P06746 | 5/20 | 0.80 |
| ▸ | CDK2 | P24941 | 3/20 | 0.80 |
| ▸ | AHR | P35869 | 1/20 | 0.80 |
| ▸ | GSK3B | P49841 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.77 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 4/20 | 0.66 |
| ▸ | ALPL | P05186 | 2/20 | 0.66 |
| ▸ | INSR | P06213 | 2/20 | 0.66 |
| ▸ | G6PD | P11413 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363974 | 1.00 | MEN1 (0.80) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL3363971 | 1.00 | MEN1 (0.80) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL3364832 | 0.89 | MEN1 (1.00) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL3364834 | 0.89 | MEN1 (1.00) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL12990149 | 0.89 | MEN1 (1.00) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL23752472 | 0.87 | GSK3B (1.00) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL3904134 | 0.83 | IGF1R (0.72) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL13388762 | 0.83 | IGF1R (0.72) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL6389114 | 0.83 | PIK3CG (0.79) | MEN1KMT2APOLBCDK2AHR | |
| SCHEMBL3904132 | 0.83 | IGF1R (0.72) | MEN1KMT2APOLBCDK2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | MEN1 2930/4885KMT2A 901/4885POLB 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.