Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 4/20 | 0.41 |
| ▸ | PRF1 | P14222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12973037 | 0.92 | HDAC6 (0.63) | HDAC6HDAC1NQO2CES1MLYCD | |
| SCHEMBL12973104 | 0.86 | HDAC6 (0.62) | HDAC6HDAC1NQO2HSD17B1MAPT | |
| SCHEMBL3093971 | 0.86 | HDAC6 (1.00) | HDAC6HDAC1KIF11 | |
| SCHEMBL14706472 | 0.81 | HDAC6 (0.54) | HDAC6HDAC1NQO2HSD17B1PRF1 | |
| SCHEMBL14706473 | 0.81 | HDAC6 (0.54) | HDAC6HDAC1NQO2HSD17B1PRF1 | |
| SCHEMBL14706471 | 0.81 | HDAC6 (0.54) | HDAC6HDAC1NQO2HSD17B1PRF1 | |
| SCHEMBL19056956 | 0.74 | CES1 (0.65) | HDAC6HDAC1CES1MLYCD | |
| SCHEMBL28612660 | 0.74 | HDAC6 (0.57) | HDAC6NQO2HSD17B1MAPTSMN1; SMN2 | |
| SCHEMBL14706470 | 0.74 | HDAC6 (0.47) | HDAC6HDAC1NQO2HSD17B1PRF1 | |
| SCHEMBL25451198 | 0.73 | HDAC6 (0.56) | HDAC6HDAC1NQO2HSD17B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100301314-A1 | CONJUGATED COMPOUND, NITROGENATED CONDENSED-RING COMPOUND, NITROGENATED CONDENSED-RING POLYMER, ORGANIC THIN FILM, AND ORGANIC THIN FILM ELEMENT | OSAKA UNIVERSITY (JP) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100301314-A1 | CONJUGATED COMPOUND, NITROGENATED CONDENSED-RING COMPOUND, NITROGENATED CONDENSED-RING POLYMER, ORGANIC THIN FILM, AND ORGANIC THIN FILM ELEMENT | F12, F9, C9 | HDAC6 990/4885HDAC1 1082/4885NQO2 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.