SCHEMBL1300121

SCHEMBL1300121

C/C(C(=O)O)=C(/C)C(=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27477351 0.89 FFAR3 (0.43) FFAR3LCKFYNLMNATHRB
SCHEMBL105998 0.84 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB
SCHEMBL10661623 0.84 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB
SCHEMBL141678 0.84 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB
SCHEMBL105999 0.84 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB
SCHEMBL10661655 0.84 FFAR3 (0.55) FFAR3LCKFYNLMNATHRB
SCHEMBL11662989 0.81 FFAR3 (0.50) FFAR3LCKFYNLMNATHRB
SCHEMBL29259774 0.81 FFAR3 (0.50) FFAR3LCKFYNLMNATHRB
SCHEMBL11528891 0.81 FFAR3 (0.50) FFAR3LCKFYNLMNATHRB
SCHEMBL11662990 0.81 FFAR3 (0.50) FFAR3LCKFYNLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023636-B2 Microorganisms and methods for the biosynthesis of propylene GENOMATICA, INC. (US) 2015-05-05 US disclosed
US-8617862-B2 Microorganisms for producing propylene and methods related thereto GENOMATICA, INC. (US) 2013-12-31 US disclosed
EP-2563926-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE Genomatica, Inc. (US) 2013-03-06 EP disclosed
US-20120329119-A1 MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO GENOMATICA, INC. 2012-12-27 US disclosed
WO-2011137198-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE GENOMATICA, INC. (US) 2011-11-03 WO disclosed
US-20110269204-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE AGAIN BIO APS (DK) 2011-11-03 US disclosed