Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 7/20 | 0.60 |
| ▸ | PPP5C | P53041 | 2/20 | 0.60 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.60 |
| ▸ | NPY4R | P50391 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11885821 | 0.79 | TFPI2 (0.59) | TFPI2PPP5CPPP2CANPY4RHTT | |
| SCHEMBL26377824 | 0.79 | TFPI2 (0.59) | TFPI2PPP5CPPP2CANPY4RHTT | |
| SCHEMBL9880170 | 0.79 | TFPI2 (0.59) | TFPI2PPP5CPPP2CANPY4RHTT | |
| SCHEMBL1572846 | 0.78 | TFPI2 (0.74) | TFPI2PPP5CPPP2CANPY4RHTT | |
| SCHEMBL20459539 | 0.77 | TFPI2 (0.56) | TFPI2PPP5CPPP2CANPY4RHTT | |
| Lb-100 SCHEMBL9880148 | 0.76 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RHTT | |
| Lb-100 SCHEMBL13311584 | 0.76 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RHTT | |
| Lb-100 SCHEMBL12390164 | 0.76 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RHTT | |
| Lb-100 SCHEMBL19512780 | 0.76 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RHTT | |
| Lb-100 SCHEMBL26377801 | 0.76 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147612-A1 | METHODS OF MODULATING CELL REGULATION BY INHIBITING P53 | LIXTE BIOTECHNOLOGY, INC. (US) | 2010-12-23 | — | — | WO | disclosed |