Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 4/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | SIK1 | P57059 | 3/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10294971 | 0.92 | AURKB (0.45) | RAD52RECQLBLMSRCAURKA | |
| SCHEMBL10294964 | 0.91 | AURKA (0.43) | RAD52RECQLBLMSRCAURKA | |
| SCHEMBL10294847 | 0.91 | AURKA (0.51) | RAD52RECQLBLMSRCAURKA | |
| SCHEMBL10294686 | 0.91 | AURKA (0.55) | SRCAURKAAURKBRIPK1KIT | |
| SCHEMBL10295060 | 0.91 | RAD52 (0.49) | RAD52RECQLBLMSRCAURKA | |
| SCHEMBL10294861 | 0.90 | AURKA (0.45) | SRCAURKAAURKBRIPK1KIT | |
| SCHEMBL10294897 | 0.90 | RAD52 (0.46) | RAD52RECQLBLMSRCAURKA | |
| SCHEMBL10294487 | 0.88 | KIT (0.41) | SRCAURKAAURKBRIPK1KIT | |
| SCHEMBL10294796 | 0.86 | AURKA (0.54) | SRCAURKAAURKBRIPK1KIT | |
| SCHEMBL10294993 | 0.84 | AURKA (0.55) | RAD52RECQLBLMSRCAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144359-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | ABRAXIS BIOSCIENCE, LLC (US) | 2010-12-16 | — | — | WO | disclosed |