Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.69 |
| ▸ | GIPR | P48546 | 7/20 | 0.69 |
| ▸ | GLP1R | P43220 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12360394 | 0.95 | GCGR (0.76) | GCGRGIPR | |
| SCHEMBL2667910 | 0.90 | GCGR (0.62) | GCGRGIPRGLP1R | |
| SCHEMBL2667299 | 0.89 | GCGR (0.61) | GCGRGIPRGLP1R | |
| SCHEMBL12360391 | 0.88 | GCGR (0.59) | GCGRGIPRGLP1R | |
| SCHEMBL2667403 | 0.87 | GCGR (0.64) | GCGRGIPRGLP1R | |
| SCHEMBL2667290 | 0.86 | GCGR (0.62) | GCGRGIPRGLP1R | |
| SCHEMBL2667293 | 0.83 | GCGR (0.57) | GCGRGIPRGLP1R | |
| SCHEMBL12360139 | 0.81 | GCGR (1.00) | GCGRGIPRGLP1RKCNH2 | |
| SCHEMBL12360054 | 0.81 | GCGR (1.00) | GCGRGIPR | |
| SCHEMBL2667356 | 0.80 | GCGR (0.60) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |