Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.53 |
| ▸ | GIPR | P48546 | 5/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003163 | 0.85 | GCGR (0.66) | GCGRGIPRPTGDR2 | |
| SCHEMBL12360326 | 0.81 | GCGR (0.68) | GCGRGIPR | |
| SCHEMBL12360330 | 0.80 | GCGR (0.66) | GCGRGIPR | |
| SCHEMBL9071633 | 0.73 | GCGR (0.81) | GCGRGIPR | |
| SCHEMBL2667313 | 0.73 | GCGR (0.76) | GCGRGIPR | |
| SCHEMBL9071542 | 0.72 | GCGR (0.82) | GCGRGIPR | |
| SCHEMBL12360311 | 0.72 | GCGR (0.77) | GCGRGIPR | |
| SCHEMBL12360160 | 0.71 | GCGR (0.89) | GCGRGIPR | |
| SCHEMBL12360441 | 0.71 | GCGR (0.69) | GCGRGIPR | |
| SCHEMBL2667878 | 0.71 | GCGR (0.69) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |