Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540606 | 1.00 | IDO1 (0.50) | IDO1HTR2APRCPCHRNA7PDPK1 | |
| SCHEMBL13115630 | 0.89 | HTR2A (0.52) | IDO1HTR2APRCPPDPK1 | |
| SCHEMBL11498923 | 0.89 | HTR2A (0.52) | IDO1HTR2APRCPPDPK1 | |
| SCHEMBL3296406 | 0.85 | IDO1 (0.49) | IDO1PRCPCHRNA7PDPK1GID4 | |
| SCHEMBL3000155 | 0.85 | IDO1 (0.49) | IDO1PRCPCHRNA7PDPK1GID4 | |
| Trifluoromethanesulfonic Acid SCHEMBL28355596 | 0.85 | IDO1 (0.38) | IDO1HTR2A | |
| SCHEMBL9500102 | 0.82 | IDO1 (0.50) | IDO1CHRNA7 | |
| SCHEMBL4081534 | 0.82 | IDO1 (0.46) | IDO1PRCPCHRNA7PDPK1GID4 | |
| Hydrogen Peroxide SCHEMBL9456544 | 0.82 | IDO1 (0.46) | IDO1PRCP | |
| SCHEMBL29463951 | 0.79 | IDO1 (0.44) | IDO1PRCPCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742052-B2 | Polyurea compound | NUPLEX RESINS B.V. (NL) | 2014-06-03 | — | — | US | disclosed |
| US-7851530-B2 | High viscosity at low shear; for use as sag control agents in coatings, paints, cosmetics, mining, paper, textile industries; Urea reaction product of isocyanate such as hexamethylene diisocyanate with high enantiomeric excess of optically active methylamines such as alpha-methylbenzylamine | NUPLEX RESINS B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| EP-1641887-B1 | CARBON-SUBSTITUTED METHYL AMINE DERIVATIVES AND THEIR USE AS A RHEOLOGY CONTROL AGENT | NUPLEX RESINS BV (NL) | 2010-10-06 | — | — | EP | disclosed |