SCHEMBL13008367

SCHEMBL13008367

CN1c2ccccc2N(c2ccc3c(-c4cccc5ccccc45)c4cc(N5c6ccccc6N(C)c6ccccc65)ccc4c(-c4ccc5ccccc5c4)c3c2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.43
MET P08581 1/20 0.36
PIM1 P11309 2/20 0.35
PDE6D O43924 1/20 0.33
POLB P06746 1/20 0.33
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
CNR2 P34972 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSD11B1 P28845 1/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
SOS1 Q07889 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13427622 0.98 AKT1 (0.41) AKT1METPIM1PDE6DPOLB
SCHEMBL13427589 0.96 AKT1 (0.41) AKT1METPIM1PDE6DPOLB
SCHEMBL13008771 0.96 AKT1 (0.39) AKT1METPIM1PDE6DPOLB
SCHEMBL13008766 0.96 AKT1 (0.41) AKT1METPIM1PDE6DPOLB
SCHEMBL13427596 0.94 AKT1 (0.42) AKT1METPIM1PDE6DPOLB
SCHEMBL13427625 0.94 AKT1 (0.42) AKT1METPIM1PDE6DPOLB
SCHEMBL13427593 0.94 AKT1 (0.42) AKT1METPIM1PDE6DPOLB
SCHEMBL13427598 0.91 AKT1 (0.40) AKT1METPDE6DALDH1A1MAPT
SCHEMBL13008769 0.91 POLB (0.34) AKT1METPDE6DPOLBMAPT
SCHEMBL13427620 0.91 PDE6D (0.40) AKT1PDE6DPOLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256176-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-12-01 EP disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A AKT1 3459/4885MET 3253/4885PIM1 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.