SCHEMBL13008786

SCHEMBL13008786

c1ccc2c(c1)Cc1ccccc1N2c1ccc2c(-c3ccccc3-c3cccc4ccccc34)c3cc(N4c5ccccc5Cc5ccccc54)ccc3c(-c3ccccc3-c3cccc4ccccc34)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.33
HPGD P15428 1/20 0.33
HTR1A P08908 10/20 0.32
HTR7 P34969 8/20 0.32
CASP6 P55212 2/20 0.31
SOS1 Q07889 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
HTR3E A5X5Y0 1/20 0.30
HTR3B O95264 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
NCF1 P14598 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13008231 0.99 POLB (0.35) POLBCTDSP1HPGDHTR1AHTR7
SCHEMBL13426910 0.95 POLB (0.38) POLBCTDSP1HPGDHTR1AHTR7
SCHEMBL13009315 0.94 PDE6D (0.33) POLBCTDSP1HPGDSOS1GPR84
SCHEMBL13428128 0.92 POLB (0.36) POLBHPGDHTR1AHTR7SOS1
SCHEMBL13009190 0.91 POLB (0.35) POLBHPGDHTR1AHTR7SOS1
SCHEMBL13008239 0.91 PIM1 (0.35) POLBHPGDCYP1A2
SCHEMBL13009393 0.89 PDE6D (0.34) POLBCTDSP1HPGDSOS1TSHR
SCHEMBL13008245 0.89 POLB (0.34) POLBCTDSP1HPGDHTR1AHTR7
SCHEMBL13008789 0.89 PDE6D (0.34) POLBCTDSP1HPGDSOS1TSHR
SCHEMBL13427030 0.88 CA12 (0.33) POLBCTDSP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256176-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-12-01 EP disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A POLB 913/4885CTDSP1 2078/4885HPGD 4470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.