Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372729 | 0.78 | TSHR (0.39) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL28948545 | 0.78 | TSHR (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL27559098 | 0.78 | SLC22A6 (0.43) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL249850 | 0.78 | TSHR (0.39) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL4397555 | 0.78 | TSHR (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL29799742 | 0.78 | TSHR (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL23913764 | 0.77 | SLC22A6 (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL20711453 | 0.77 | SLC22A6 (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL1572820 | 0.77 | SLC22A6 (0.41) | TSHRALDH1A1ADRA1AHMGCRCHRM1 | |
| SCHEMBL31504495 | 0.77 | GRIK1 (0.46) | TSHRALDH1A1TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023636-B2 | Microorganisms and methods for the biosynthesis of propylene | GENOMATICA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8617862-B2 | Microorganisms for producing propylene and methods related thereto | GENOMATICA, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2563926-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | Genomatica, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20120329119-A1 | MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO | GENOMATICA, INC. | 2012-12-27 | — | — | US | disclosed |
| WO-2011137198-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | GENOMATICA, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110269204-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | AGAIN BIO APS (DK) | 2011-11-03 | — | — | US | disclosed |
| EP-2178846-A1 | ROSUVASTATIN INTERMEDIATES AND THEIR PREPARATION | Teva Pharmaceutical Industries Ltd. (IL) | 2010-04-28 | — | — | EP | disclosed |
| US-20090069563-A1 | Rosuvastatin intermediates and their preparation | TEVA PHARMACEUTICALS USA, INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009009152-A1 | ROSUVASTATIN INTERMEDIATES AND THEIR PREPARATION | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-01-15 | — | — | WO | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069563-A1 | Rosuvastatin intermediates and their preparation | HMGCR, PCSK9, PCSK7 | TSHR 4255/4885ALDH1A1 2082/4885ADRA1A 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.