Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648263 | 0.87 | — | — | |
| SCHEMBL2143102 | 0.83 | — | — | |
| SCHEMBL2143097 | 0.83 | — | — | |
| SCHEMBL5881401 | 0.79 | GRIK1 (0.37) | GRIK1GRIK2CTSK | |
| SCHEMBL13001269 | 0.79 | GRIK1 (0.37) | GRIK1GRIK2CTSK | |
| SCHEMBL5868513 | 0.78 | — | — | |
| SCHEMBL5214456 | 0.78 | — | — | |
| SCHEMBL5868510 | 0.78 | — | — | |
| SCHEMBL5214461 | 0.78 | — | — | |
| SCHEMBL11193975 | 0.77 | FFAR1 (0.56) | FFAR1FFAR4NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648922-B1 | SPATIALLY-DEFINED MACROCYCLIC COMPOUNDS USEFUL FOR DRUG DISCOVERY | TRANZYME PHARMA INC (CA) | 2010-12-01 | — | — | EP | disclosed |