Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.83 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.83 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606675 | 0.94 | S1PR1 (0.74) | S1PR1S1PR5 | |
| SCHEMBL13013305 | 0.92 | S1PR1 (0.81) | S1PR1S1PR5 | |
| SCHEMBL2125026 | 0.91 | S1PR1 (1.00) | S1PR1S1PR5S1PR3 | |
| SCHEMBL13012839 | 0.91 | S1PR1 (0.68) | S1PR1S1PR5 | |
| SCHEMBL2606676 | 0.91 | S1PR1 (0.69) | S1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL2122860 | 0.90 | S1PR1 (0.98) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2128493 | 0.90 | S1PR1 (1.00) | S1PR1S1PR5S1PR3 | |
| SCHEMBL13012903 | 0.89 | S1PR1 (0.67) | S1PR1S1PR5 | |
| Trifluoroacetic Acid SCHEMBL2125035 | 0.87 | S1PR1 (0.92) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2606673 | 0.86 | S1PR1 (0.67) | S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146104-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |