Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013307 | 0.94 | S1PR1 (0.56) | S1PR1S1PR5DPP4DPP8DPP9 | |
| SCHEMBL2130417 | 0.90 | S1PR1 (0.69) | S1PR1S1PR5 | |
| SCHEMBL2125645 | 0.90 | S1PR1 (0.69) | S1PR1S1PR5 | |
| SCHEMBL13012924 | 0.89 | S1PR1 (0.60) | S1PR1S1PR5DPP4DPP8DPP9 | |
| SCHEMBL13013304 | 0.89 | S1PR1 (0.56) | S1PR1S1PR5DPP4DPP8DPP9 | |
| SCHEMBL13013263 | 0.87 | S1PR1 (0.54) | S1PR1S1PR5DPP4DPP8DPP9 | |
| SCHEMBL2130215 | 0.85 | S1PR1 (0.69) | S1PR1S1PR5 | |
| SCHEMBL13013431 | 0.83 | S1PR1 (0.58) | S1PR1S1PR5 | |
| SCHEMBL13013305 | 0.82 | S1PR1 (0.81) | S1PR1S1PR5 | |
| SCHEMBL13012839 | 0.81 | S1PR1 (0.68) | S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146104-A1 | THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |