Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279274 | 0.75 | PRKCI (0.33) | PRKCICCNKCDK12 | |
| SCHEMBL3414426 | 0.74 | CHUK (0.43) | PRKCICCNKCDK12 | |
| SCHEMBL32671221 | 0.70 | PRKCI (0.44) | PRKCICCNKCDK12 | |
| SCHEMBL2239319 | 0.67 | CHUK (0.51) | PRKCICCNKCDK12 | |
| SCHEMBL20839750 | 0.66 | CCNK (0.57) | PRKCICCNKCDK12 | |
| SCHEMBL3416746 | 0.65 | PRKCI (0.40) | PRKCICCNKCDK12 | |
| SCHEMBL31634054 | 0.64 | PRKCI (0.48) | PRKCI | |
| SCHEMBL4319429 | 0.64 | PRKCI (0.48) | PRKCI | |
| SCHEMBL13505099 | 0.64 | PRKCI (0.39) | PRKCICCNKCDK12 | |
| SCHEMBL3418231 | 0.64 | PRKCI (0.40) | PRKCICCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069341-B1 | PYRROLO[2, 3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS IKK2 INHIBITORS | GLAXO GROUP LTD (GB) | 2010-12-29 | — | — | EP | disclosed |