Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.54 |
| ▸ | RELA | Q04206 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999293 | 0.84 | TSHR (0.61) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL15219102 | 0.82 | TSHR (0.56) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL659214 | 0.82 | TSHR (0.71) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL1620050 | 0.81 | TSHR (0.54) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL11924524 | 0.79 | TSHR (0.63) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL1620051 | 0.79 | TSHR (0.52) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL3658362 | 0.79 | TSHR (0.52) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL13035816 | 0.79 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL7955024 | 0.79 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL24026375 | 0.78 | PARP1 (0.67) | TSHRRAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546563-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| US-8546563-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| US-20100331304-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331304-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | TSHR 876/4885RAB9A 2264/4885SMN1; SMN2 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.