Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 19/20 | 0.61 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342967 | 0.88 | CCR9 (0.78) | CCR9CCR2 | |
| SCHEMBL344940 | 0.80 | CCR9 (0.78) | CCR9CCR2 | |
| SCHEMBL343310 | 0.78 | CCR9 (0.70) | CCR9CCR2 | |
| SCHEMBL343780 | 0.77 | CCR9 (0.78) | CCR9CCR2 | |
| SCHEMBL343333 | 0.77 | CCR9 (0.82) | CCR9CCR2 | |
| SCHEMBL10249468 | 0.76 | CCR9 (1.00) | CCR9CCR2 | |
| SCHEMBL344260 | 0.75 | CCR9 (1.00) | CCR9CCR2 | |
| SCHEMBL13663117 | 0.75 | CCR9 (0.85) | CCR9CCR2 | |
| SCHEMBL13017227 | 0.75 | CCR9 (0.87) | CCR9CCR2 | |
| SCHEMBL344540 | 0.74 | CCR9 (1.00) | CCR9CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256116-A2 | Aryl sulfonamides | ChemoCentryx, Inc. (US) | 2010-12-01 | — | — | EP | disclosed |