Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 17/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343754 | 0.90 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344987 | 0.90 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344864 | 0.89 | CCR9 (0.83) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343770 | 0.88 | CCR9 (0.75) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL11937069 | 0.88 | CCR9 (0.85) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343840 | 0.87 | CCR9 (0.80) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL13146482 | 0.87 | CCR9 (0.79) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL15906627 | 0.86 | CCR9 (0.78) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL12359492 | 0.86 | CCR9 (0.84) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL21202549 | 0.84 | CCR9 (0.74) | CCR9LMNAHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256116-A2 | Aryl sulfonamides | ChemoCentryx, Inc. (US) | 2010-12-01 | — | — | EP | disclosed |