⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517018 | 1.00 | — | — | |
| SCHEMBL10203797 | 1.00 | — | — | |
| SCHEMBL17517019 | 1.00 | — | — | |
| SCHEMBL13211870 | 1.00 | — | — | |
| SCHEMBL19122090 | 1.00 | — | — | |
| SCHEMBL19062931 | 1.00 | — | — | |
| SCHEMBL8061439 | 1.00 | — | — | |
| SCHEMBL18634424 | 1.00 | — | — | |
| SCHEMBL29332287 | 0.83 | — | — | |
| SCHEMBL11917825 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
| US-11718610-B2 | Compounds containing benzosultam | MEDSHINE DISCOVERY INC. (CN) | 2023-08-08 | — | — | US | disclosed |
| US-20230183230-A1 | COMPOUNDS CONTAINING BENZOSULTAM | SUZHOU GENHOUSE BIO CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| EP-3592741-B1 | NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2023-02-15 | — | — | EP | disclosed |
| US-11339177-B2 | Heteroaryl compounds as inhibitors of necrosis, composition and method using the same | ACCRO BIOSCIENCE (HK) LIMITED (HK) | 2022-05-24 | — | — | US | disclosed |
| US-20210155635-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF NECROSIS, COMPOSITION AND METHOD USING THE SAME | ACCRO BIOSCIENCE (HK) LIMITED (HK) | 2021-05-27 | — | — | US | disclosed |
| EP-1934238-B1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2258708-A1 | Macrolide compounds endowed with antiinflammatory activity | Zambon S.p.A. (IT) | 2010-12-08 | — | — | EP | disclosed |