SCHEMBL130185

SCHEMBL130185

C=C[CH]c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8810777 1.00
SCHEMBL1389123 1.00
Butadiene SCHEMBL1396862 0.81 MEN1 (0.61)
SCHEMBL29371456 0.80
SCHEMBL15193 0.80
SCHEMBL9359592 0.80 MEN1 (0.67)
SCHEMBL455189 0.79 MEN1 (0.65)
SCHEMBL8541538 0.79 MEN1 (0.65)
Butadiene SCHEMBL27667790 0.79 MEN1 (0.58)
Butadiene SCHEMBL377374 0.79 MEN1 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A9 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-12-27 EP claimed
US-11840549-B2 Bisphosphonate quinolone conjugates and uses thereof BIOVINC, LLC (US) 2023-12-12 US claimed
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP claimed
EP-4225275-A1 LIPID FORMULATIONS OF TRIAZOLOQUINAZOLINONE COMPOUNDS Gabather AB (SE) 2023-08-16 EP claimed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP claimed
US-20230110003-A1 PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) Valo Health, LLC 2023-04-13 US claimed
EP-4136078-A1 BENZIMIDAZOLE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-02-22 EP claimed
EP-4136081-A1 SULFAMOYLAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-02-22 EP claimed
WO-2022074457-A1 LIPID FORMULATIONS OF TRIAZOLOQUINAZOLINONE COMPOUNDS GABATHER AB (SE) 2022-04-14 WO claimed
US-20210369849-A1 BONE TARGETED ANTIMICROBIAL OXAZOLIDINONE RELATED COMPOUNDS, FORMULATIONS THEREOF, AND USES THEREOF EBETINO FRANK HALLOCK (US) 2021-12-02 US claimed
US-5095015-A G-aminobutyric acid, anticonvulsants, tranquilizers, sleep disorders NEUROGEN CORPORATION (US) 1992-03-10 US claimed
WO-1992000296-A1 CERTAIN AZACYCLOALKYL IMIDAZOPYRIMIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1992-01-09 WO claimed
WO-1991019735-A1 LIBRARIES OF MODIFIED PEPTIDES WITH PROTEASE RESISTANCE BARTLETT PAUL A (US) 1991-12-26 WO claimed
US-4931379-A ADDITION POLYMERS HAVING PENDANT ACID-LABILE GROUPS, E.G CARBONATES, AND SIDECHAINS FOR ADDED STABILITY; SEMICONDUCTORS; MICROLITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1990-06-05 US claimed
EP-0331421-A2 Hollow polymer particles, process for production thereof, and use thereof as pigment JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-09-06 EP claimed
EP-0300882-A2 Novel 5-Aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones ICI AMERICAS INC. (US) 1989-01-25 EP claimed
US-4791120-A ANALGESICS THE BOC GROUP, INC. (US) 1988-12-13 US claimed
US-4735951-A Novel 4-hydroxy-3-quinoline-carboxylates having analgesic and anti-inflammatory activity ROUSSEL UCLAF (FR) 1988-04-05 US claimed
CN-87103572-A From nicotinic acid derivates is the mycocide and the preparation thereof of base 1988-01-13 CN claimed
CN-87102879-A Benzhydryl compounds as herbicide antidotes 1987-10-28 CN claimed